MatinGloire is dedicated to build trust and conviction in our products and believe that it is customers right to know as much as possible about our products. Skin and hair define our outer identity and hence one should be fully aware of what is used in our products beyond just list of ingredients. Let us walk through the ingredients and understand the what and how of our products.

Disclaimer – Products offered at MatinGlorie are not intended to diagnose, treat, or cure any illness or severe skin diseases. The information mentioned here is for YOU to be aware of the scientific and clinical information available in public about the ingredients used in our products and efforts we have taken to study them while designing our products.

MATINGLORIE's Clear and Natural Probiotic Anti-Pollution moisturizing cream.

This advanced cream is created for skin which frequently gets exposed to pollution, dust, and microorganisms. In most of the cities due to proximity to people and other objects, our skin gets exposed to contaminants with lot of harmful microorganisms. Additionally, we sweat more in cities due to high humidity and, city air contains pollutants and dust. Together, this causes skin irritation, rashes, and acne. Exposure to pollutants makes the skin dry, dull, and dehydrated. We have designed this cream from natures best ingredients which will provide protection from harmful microorganisms, deep moisturization, reduce effect of pollution, provide fast healing to irritated skin and importantly keep your skin shiny, bright and young.

One of the most common skin diseases is acne vulgaris, a chronic inflammatory skin condition of the skin glands which secrete fluids (sebaceous follicles and glands). The cause of acne vulgaris is multifactorial, with increased sebum production, alteration in the quality of sebum lipids, dysregulation of the hormone environment, and keratin build up around hair follicles causing skin bumps (follicular hyperkeratinization) as contributing factors. In addition, specific strains of the bacteria Cutibacterium acnes (formerly known as Propionibacterium acnes) are involved in the inflammation of the skin, especially by secreting lipase enzymes that can metabolize sebum into free fatty acids, which leads to skin irritation.

Lactobacillus (prevents bacterial growth) – Probiotics are micro-organisms which administered in adequate amounts, confer a health benefit on the host. Lactobacillus is one of the most common types of probiotics and can be found in fermented foods, yogurt and supplements. Its name gives an indication of what it produces — lactic acid. It does this by producing an enzyme called lactase. Lactase breaks down lactose, a sugar found in milk, into lactic acid. Lactobacillus is also a component of our normal healthy microflora of skin and gut. But, due to repeated exposure to surfactants, pollution, dust and makeup, we lose this healthy bacterium. In a study, lactobacilli were tested for antimicrobial effects on the growth of C. acnes and all strains of lactobacilli inhibited the growth of C. acnes. In addition, the strains of lactobacilli were able to significantly reduce the lipase activity of C. acnes. These lipase enzymes are involved in inflammation of the skin induced by C. acnes, because they metabolize sebum into free fatty acids, which may lead to skin irritation. In a clinical study, lotion containing Lactobacillus acidophilus significantly reduced the symptoms of acne by more than 75% indicating clearing of C. acnes. The mechanism by which C. acnes are cleared by Lactobacillus acidophilus is by inhibiting a compound called Porphyrins. Porphyrins are intermediate metabolites produced by C. acnes known to be proinflammatory, with high levels linked to inflammatory skin diseases.

Alpha-Bisabolol (anti-irritant, healing, brightening) – Bisabolol was first obtained from Matricaria chamomilla, commonly known as German chamomile. The available literature indicates that this plant is popularly used in traditional medicine for potential health benefits and general wellbeing. There is an account of Bisabolol’s effect found in some of the clinical and scientific studies. In a clinical trial the effectiveness of Bisabolol was evaluated against skin condition like eczema and atopic dermatitis in children. Results concluded that Bisabolol based cream reduced skin flashes compared to baseline showed by a significant decrease in the affected skin surface area. In another study, the integration of Bisabolol in a formulation designed for the treatment of melasma showed enhancement in the recovered melasmatic area measured by imaging techniques compared with control. A statistical significance was seen in patients’ satisfaction in terms of improved facial texture, skin oiliness, brightness, hydrated skin, and overall appearance following the treatment. Bisabolol has also been demonstrated to exert a healing effect on wounds. In an in-vivo study, a remarkable action of Bisabolol was observed on migration of cells that secrete collagen proteins which help maintain the structural framework of skin tissue. This hastened the healing process and significantly improved the wound healing.

AQUAXYL (deep moisturization) – AQUAXYL is a patented moisturizing agent from SEPPIC, France which optimizes the skins’ water flow. It is a “Anti-dehydration shield” and acts by reinforcing the synthesis of essential lipids and proteins involved in the organization of the outer layer, stratum corneum. Interestingly, it is developed from simple natural sugar-based Ingredient into a functional structure (Xylitylglucoside-Anhydroxylitol-Xylitol, XAX). It is scientifically and clinically proven that AQUAXYL increases hydration by 13.5% after just 24 hours and prevents loss of transepidermal water loss (TEWL) by 15.4% after 8 days. It also improves peeling or flaking skin, which is a natural process that occurs when the outer layer of skin replaces itself. Thus, it contributes to the improvement of skin barrier function. Most importantly, AQUAXYL treatment showed increased contents of ceramides, hyaluronic acid and chondroitin sulfate. Ceramides are a complex group of waxy lipid molecules that help keep skin cells together, helps keep out irritants and bacteria and keep in moisture. Hyaluronic acid is a sugar molecule that occurs naturally in the body, can absorb over 1,000 times its weight in water, keeping skin moisturized and keeps skin elastic and flexible. Chondroitin sulphate is an important structural component of the skin ecosystem where it increases the proliferation of skin cells and induce the expression of type I procollagen. All these are components of skin natural moisturizing system which helps keep moisture locked inside.

Opuntia Ficus (Moisturization, antimicrobial) – Prickly pear (Opuntia ficus indica) a plant from the Cactaceae family is attracting growing interest due to its richness in active compounds, precisely in the cladodes, roots, flowers, fruits, and seeds. Traditionally, O. ficus-indica are commonly used as a food source and several studies have been conducted showing increased production of gastric mucus, wound healing and, antioxidant properties. It also a source of calcium oxalate that have an important role in water retention and osmotic pressure regulation. Thus, primarily it shows an excellent moisturizing properties and, one of the clinical studies also proves this. In this study a lotion formulation which included extract of Opuntia ficus showed statistically significant increase of skin hydration within 5 hours after the application. There was significant moisturizing effect of the outer skin layer and the barrier function and reduction in Trans epidermal water loss (TEWL) due to the presence of carbohydrates and flavonoids in its chemical composition. Apart from the moisturizing effect, Opuntia ficus has shown good antimicrobial effect on varied types of germs including bacteria and fungus. In one of the in-vitro studies, the whole fruit extract (including seeds) showed significant reduction in microbial load including Enerobacter, Candida yeast and Aspergillus fungus.

Tripeptides (anti-aging) – The tripepdide used in this cream is patented product from DSM Nutritional Products, Kaiseraugst, Switzerland. This tripeptide is glycerine-based, aqueous peptide solution and used as a bioactive ingredient to reduce the most visible signs of ageing. In the in-vitro tests on human skin cells, the solution stimulates biosynthesis of hyaluronic acid, a natural moisturizer in the dermis, and increases expression of the proteoglycans, decorin and lumican. Hyaluronic acid (HA) is natural compound found in skin which can bind up to 1,000 times its own weight of water to form a gel-like cushion in the layers of the skin. As skin ages, it loses the ability to replace the normal loss of dermal HA and the decline in HA content in the skin is a major factor in the visible effects of ageing. Decorin and lumican are two important complex protein structures within the dermis. Their core protein binds to collagen fibrils which bundle together to form the collagen fibres and keep them organized and in straight chain. This characteristic of collagen structure defines the tone and firmness of our skin. Thus, the tripeptide in the cream improves and maintains the structure of collagen complex and hence keeps the skin supple, smooth and young looking. In a clinical study emulsion containing the tripeptide solution was applied twice daily to the face and forearms of 41 female volunteers. After around 50 days, skin tension and tonicity were found to be significantly increased in 84% of subjects. The tripeptide also had a significant and visible effect on the outlines of the face, reducing skin sagging in 74% and the double chin in 58% of subjects.

Squalane (emollient, anti-oxidant, neutralizes pollution gases) – Squalene (with an “e”) is a fatty oil produced naturally by our own skin cells. It is also naturally present in olives, rice bran, and sugarcane. But the amount of squalene our body produces declines with age. Squalene is not a very stable compound and quickly oxidizes. It is stabilized by hydrogenating it in to Squalane (with an “a”). Hydrogenation makes the oil more skin-friendly and helps increase its shelf life. One of nature’s great emollients, squalene is quickly and efficiently absorbed deep into the skin, restoring healthy suppleness and flexibility, giving skin a shine without leaving an oily residue. Squalene is also a natural antioxidant and has antitumor properties, protecting your skin from carcinogens. After exposure to oxidative stress such as sunlight, squalene functions as an efficient inhibitor of reactive oxygen species and prevents the corresponding lipid peroxidation at the human skin. Interestingly, researchers have found that squalene could potentially play a role in increasing the activity of certain types of reactive species that can ultimately help oxidize pollutant gases. Gases like nitrogen oxide compounds interact with volatile organic compounds (VOCs) upon ultraviolet (UV) photoactivation to generate ground‐level ozone which induces skin allergies and inflammation. In human subjects exposed to ozone in a climate-controlled environment, researchers noted that it reacted with the lipid squalene in the subjects’ skin, and led to the formation of compound called 6-MHO. This 6-MHO subsequently generates Hydroxyl ion which could create a protective effect. It could be that squalene not only reduces oxidative damage to the skin but that it could also have a positive effect on pollutant gases like ozone.

References:

1. Porphyrin Production and Regulation in Cutaneous Propionibacteria, RESEARCH ARTICLE, Molecular Biology and Physiology, January/February 2020 Volume 5 Issue 1

2. In vivo Evaluation of the Antagonistic Effect of Lactobacillus acidophilus against Propionobacterium acnes in the Treatment of Acne, Pure Appl Microbiol, September 2019

3. Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of alpha-Bisabolol, 2022, Nutrients.

4. Effect of a Simple Sugar-based Ingredient on Skin Moisturization: Biological Mode of Action and Clinical Effects, 2023, Asian J Beauty Cosmetol

5. https://www.seppic.com/en/wesource/aquaxyl

6. Use of Opuntia ficus-indica (L.) Mill extracts from Brazilian Caatinga as an alternative of natural moisturizer in cosmetic formulations, 2016, Brazilian Journal of Pharmaceutical Sciences

7. https://www.personalcaremagazine.com/story/6594/new-peptide-promotes-skin-firming-and-remodelling

8. Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology, 2009, Molecules

9. Biological importance and applications of squalene and squalane, 2012, Adv Food Nutr Res