MatinGloire is dedicated to build trust and conviction in our products and believe that it is customers right to know as much as possible about our products. Skin and hair define our outer identity and hence one should be fully aware of what is used in our products beyond just list of ingredients. Let us walk through the ingredients and understand the what and how of our products.

Disclaimer – Products offered at MatinGlorie are not intended to diagnose, treat, or cure any illness or severe skin diseases. The information mentioned here is for YOU to be aware of the scientific and clinical information available in public about the ingredients used in our products and efforts we have taken to study them while designing our products.

MATINGLORIE's Clear and Natural Ziro cream

Most of the people who have dry skin also suffer from cracked heels, corn, callus, and hardened skin over ankle bone. Cracked heals are caused by dry, thick skin around the heels that cracks due to pressure on the fat pad under the heel. The skin on the feet is often drier than the skin on the rest of the body because there are no oil glands on the soles of the feet. Dry skin can be made worse by low humidity, cold weather, hot showers, indoor heating and most importantly weight gain and nutrient deficiencies.

It aggravates by wearing open-heeled shoes, like sandals or thongs. Hard, unsupportive shoes can also contribute to cracked heels. One more reason for cracked heels is due to standing for long periods of time, especially on hard floors. Other more severe conditions aggravating cracked heels is Xerosis, Psoriasis, Dermatitis, Eczema, Keratosis, Cuticles around Nails, Corn & Callus, Ichthyosis Vulgaris, Scales and Dead Skin. A common problem, especially in women is pigmentation and small bumps on the arms around bicep and triceps area called Keratosis pilaris. Well, that is where our advanced cream comes to your rescue.

The super active ingredients will gently exfoliate, provide deep hydration, calm the itchiness and redness, and brighten your skin leaving the affected area look healed, even, soft, smooth, glowing and beautiful. Our cream is also effective in relieving symptoms of psoriasis, eczema, xerosis and other dermatitis and provide glow. A major challenge in dermal application is that the epidermis is covered by a thin layer called ‘stratum corneum’ which acts as a barrier and provides us protection from outside environment. Thus, few compounds can be transported across into epidermis. We have used a unique technology where we have encapsulated the active ingredient in small nanospheres (novel polymeric technology) which can cross the epidermis and deliver the active ingredients where it is necessary. Let us dive in to know more about the ingredients used in our cream.

Glycolic acid (Exfoliating, Brightening) – Glycolic acid (GA) is a type of Alpha Hydroxy Acids (AHA). These are a type of exfoliating compounds naturally occurring in sugarcane (glycolic acid), milk (lactic acid), and fruit (citric acid). GA is a compound that break down the outer hard layer of the skin and promote the shedding of dead skin cells (keratolytic). It also exhibits anti-inflammatory and antioxidant effects. Glycolic acid gently targets the cells of outer skin (corneocytes) by enhancing breakdown and decreasing gluiness between them, causing peeling or shedding of scales called desquamation. Specifically, GA obtained from sugarcane is used in this cream as it has the smallest molecular weight amongst all the alpha-hydroxy acids and penetrates skin easily. GA is also used to treat serious skin conditions such as ichthyosis, xeroderma, psoriasis, hyperpigmentation disorders, lentigines, melasma, and seborrheic keratoses. It is also reported to stimulate collagen production, improving the quality of elastic skin fibers and an inhibitory effect on melanin synthesis thus providing a supple and bright texture.

Urea (Natural Moisturizing Factor) – Urea is a hygroscopic molecule (capable of absorbing water) present in the epidermis as a component of the natural moisturizing factor (NMF) and is essential for the adequate hydration and integrity of the stratum corneum. Hardened dry skin nearly always starts as dry skin which occurs mostly by standing on our feet for long time. The dry skin can then turn into hardened dry skin, and that means it can become particularly uncomfortable and lead to compromised lifestyle. Multiple clinical trials on the use of urea containing formulations have shown significant clinical improvement in many of the dry skin disorders presenting with scaly and dry skin. Urea increases water retention and the resistance of the stratum corneum against osmotic stress. Furthermore, urea can act as an endogenous humectant replacing water in low humidity conditions like hot summers and even cold winters. Urea also plays a fundamental role in regulating skin cell proliferation, the skin’s barrier function and antimicrobial defense. Urea induces the expression of filaggrin, loricrin and transglutaminase-1, i.e., genes which are important for skin cell differentiation and thus skin barrier function.

Olive extract (Antioxidant) – Olive oil is a liquid fat obtained by pressing whole olives, the fruit of Olea europaea, a traditional tree crop of the Mediterranean Basin, and extracting the oil. Olive oil and olive leaf extract is well known for its amazing moisturizing, antioxidant, and anti-inflammatory properties. It contains a high amount of omega 3 fatty acid which gives it these properties. It contains oleuropein and other bioactive phenolic compounds which are identified to have various medical properties. Olive oil also contains many vitamins like A, D, E and K. These vitamins provide skin with nutrition and amazing anti-oxidant effect. It is also postulated that the phenolic compounds present in Olive oil may also accelerate the healing process of wounds. In a clinical trial on diabetic patients with foot ulcers, it was shown that olive oil treatment significantly accelerated the ulcer healing process by potentially improving blood flow to the tissue and reduce inflammation in the wound area. Phenolic compounds present in extra virgin olive could have a beneficial effect on skin regeneration.

Oats flour (Cleansing, Anti-itch agent) – Oat (Avena sativa) is distinct among the cereals due to its multifunctional characteristics and nutritional profile. Oatmeal is a natural product that holds an excellent safety record and a long history in the treatment of disease, especially in dermatology. Studies have shown that oatmeal extract can inhibit the release and activity of compounds which induces inflammation and the release of proinflammatory cytokines and histamine which are well known for causing inflammatory skin conditions. Avenacins are phenolic esters in oat which structurally belonging to saponins. Saponins have a soap-like action and so are mostly responsible for the cleansing activity of oat. Dirt and dust sticks to oatmeal, not to the skin, allowing them to be washed away more easily. A variety of functional properties make oats as a cleanser, buffer, as well as a soothing agent. Studies have demonstrated that topical formulation of natural oats, improves symptoms of severe skin conditions like psoriasis and eczema by restoring the cutaneous barrier. In a double-blinded, randomized patch study, researchers showed that topical colloidal oats grains assist in the management of mild atopic dermatitis in children. The overall itchiness and dryness reduced and quality of life improved in those children.

Ectoine (Natural Osmotic Stabilizer) – Evolution, through millions of years make microorganisms, animals and plants adapt to environment around them. One such environment is extreme saline water bodies like lakes and hot springs. It is well known that bathing in some of these water bodies provides health benefits, specially to skin. When bacteria are exposed to high saline conditions for a prolonged time, they synthesize compatible solutes known as osmolytes. These are small organic molecules that provide osmotic protection by helping to maintain appropriate pressure of the cell and, these solutes can be accumulated inside cells to extremely high concentrations. Ectoine is one such solute synthesized and accumulated by extremophiles (microorganism living in extreme environment) which acts as a biomolecule stabilizer. Ectoine acts as a chemical protectant and stabilizes the protein structure of cells. Thus, it stabilizes biomolecules against stress factors such as heating, freezing, desiccation, and UV radiation. It does this by surrounding itself and neighboring proteins or cell membranes with a water layer which is highly stable (hydrofilm). This prevents and alleviates skin conditions by external irritants like allergens, dust, pollution and infections. Thus, addition of this magical ingredient in our cream will help you protect under extreme conditions like cold, heat and exposure to dust and pollution.

References:

1. Glycolic acid peel therapy – a current review, 2013, Clinical, Cosmetic and Investigational Dermatology.

2. Glycolic acid adjusted to pH 4 stimulates collagen production and epidermal renewal without affecting levels of proinflammatory TNF-alpha in human skin explants, 2020, Journal of Cosmetic Dermatology.

3. Urea in Dermatology: A Review of its Emollient, Moisturizing, Keratolytic, Skin Barrier Enhancing and Antimicrobial Properties, 2021, Dermatol Ther (Heidelb).

4. The effect of topical olive oil on the healing of foot ulcer in patients with type 2 diabetes: a double-blind randomized clinical trial study in Iran, 2015, Journal of Diabetes & Metabolic Disorders.

5. Extra Virgin Olive Oil Phenolic Compounds Modulate the Gene Expression of Biomarkers Involved in Fibroblast Proliferation and Differentiation, 2024, Genes.

6. Oatmeal in dermatology: A brief review, Indian Journal of Dermatology, Venereology, and Leprology, 2012.

7. Safety and efficacy of personal care products containing colloidal oatmeal, 2012, Clinical, Cosmetic and Investigational Dermatology.

8. Ectoin.net

9. NhaR, LeuO, and H-NS Are Part of an Expanded Regulatory Network for Ectoine Biosynthesis Expression, 2023, Applied and Environmental Microbiology.